| 1 | Sat, Sep 05 | vs Youngstown State | W 45-13 | Kroger Field
Lexington, KY |
| 2 | Sat, Sep 12 | vs  7 Alabama | L 17-45 | Kroger Field
Lexington, KY |
| 3 | Sat, Sep 19 | @  Texas A&M | W 31-21 | Kyle Field
College Station, TX |
| 4 | Sat, Sep 26 | vs  South Alabama | W 45-21 | Kroger Field
Lexington, KY |
| 5 | Sat, Oct 03 | @  South Carolina | W 35-34 | Williams-Brice Stadium
Columbia, SC |
| 6 | Sat, Oct 10 | vs  11 LSU | | Kroger Field
Lexington, KY |
| 7 | Sat, Oct 17 | @  Oklahoma | | Memorial Stadium at Owen Field
Norman, OK |
| 8 | Sat, Oct 24 | vs  Vanderbilt | | Kroger Field
Lexington, KY |
| 8 | Sat, Oct 24 | Open Date | | Kroger Field
Lexington, KY |
| 10 | Sat, Nov 07 | @  17 Tennessee | | Neyland Stadium
Knoxville, TN |
| 11 | Sat, Nov 14 | vs  8 Florida | | Kroger Field
Lexington, KY |
| 12 | Sat, Nov 21 | @  25 Missouri | | Faurot Field
Columbia, MO |
| 13 | Sat, Nov 28 | vs  Louisville | | Kroger Field
Lexington, KY |
| 14 | Sat, Dec 05 | Open Date | |
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