| Pick | Team | Player | Position | College | Transaction |
| Round 1 |
| 1 | Cincinnati Bengals | Burrow, Joe | QB | LSU | |
| 2 | Washington Commanders | Young, Chase | DE | Ohio State | |
| 3 | Detroit Lions | Okudah, Jeff | CB | Ohio State | |
| 4 | New York Giants | Thomas, Andrew | OT | Georgia | |
| 5 | Miami Dolphins | Tagovailoa, Tua | QB | Alabama | |
| 6 | Los Angeles Chargers | Herbert, Justin | QB | Oregon | |
| 7 | Carolina Panthers | Brown, Derrick | DT | Auburn | |
| 8 | Arizona Cardinals | Simmons, Isaiah | OB | Clemson | |
| 9 | Jacksonville Jaguars | Henderson, CJ | CB | Florida | |
| 10 | Cleveland Browns | Wills Jr., Jedrick | OT | Alabama | |
| 11 | New York Jets | Becton, Mekhi | OT | Louisville | |
| 12 | Las Vegas Raiders | Ruggs III, Henry | WR | Alabama | |
| 13 | Tampa Bay Buccaneers | Wirfs, Tristan | OT | Iowa | f/Ind/SF |
| 14 | San Francisco 49ers | Kinlaw, Javon | DT | South Carolina | f/TB |
| 15 | Denver Broncos | Jeudy, Jerry | WR | Alabama | |
| 16 | Atlanta Falcons | Terrell, AJ | CB | Clemson | |
| 17 | Dallas Cowboys | Lamb, CeeDee | WR | Oklahoma | |
| 18 | Miami Dolphins | Jackson, Austin | OT | Southern Cal | f/Pit |
| 19 | Las Vegas Raiders | Arnette, Damon | CB | Ohio State | f/Chi |
| 20 | Jacksonville Jaguars | Chaisson, K'Lavon | OB | LSU | f/LAR |
| 21 | Philadelphia Eagles | Reagor, Jalen | WR | TCU | |
| 22 | Minnesota Vikings | Jefferson, Justin | WR | LSU | f/Buf |
| 23 | Los Angeles Chargers | Murray, Kenneth | IB | Oklahoma | f/NE |
| 24 | New Orleans Saints | Ruiz, Cesar | OC | Michigan | |
| 25 | San Francisco 49ers | Aiyuk, Brandon | WR | Arizona State | f/Min |
| 26 | Green Bay Packers | Love, Jordan | QB | Utah State | f/Hou/Mia |
| 27 | Seattle Seahawks | Brooks, Jordyn | IB | Texas Tech | |
| 28 | Baltimore Ravens | Queen, Patrick | IB | LSU | |
| 29 | Tennessee Titans | Wilson, Isaiah | OT | Georgia | |
| 30 | Miami Dolphins | Igbinoghene, Noah | CB | Auburn | f/GB |
| 31 | Minnesota Vikings | Gladney, Jeff | CB | TCU | f/SF |
| 32 | Kansas City Chiefs | Edwards-Helaire, Clyde | RB | LSU | |
| Round 2 |
| 33 | Cincinnati Bengals | Higgins, Tee | WR | Clemson | |
| 34 | Indianapolis Colts | Pittman Jr., Michael | WR | Southern Cal | f/Was |
| 35 | Detroit Lions | Swift, D'Andre | RB | Georgia | |
| 36 | New York Giants | McKinney, Xavier | FS | Alabama | |
| 37 | New England Patriots | Dugger, Kyle | SS | Lenoir-Rhyne | f/LAC |
| 38 | Carolina Panthers | Gross-Matos, Yetur | DE | Penn State | |
| 39 | Miami Dolphins | Hunt, Robert | OG | Louisiana | |
| 40 | Houston Texans | Blacklock, Ross | DT | TCU | f/Arz |
| 41 | Indianapolis Colts | Taylor, Jonathan | RB | Wisconsin | f/Cle |
| 42 | Jacksonville Jaguars | Shenault Jr., Laviska | WR | Colorado | |
| 43 | Chicago Bears | Kmet, Cole | TE | Notre Dame | f/LV |
| 44 | Cleveland Browns | Delpit, Grant | FS | LSU | f/Ind |
| 45 | Tampa Bay Buccaneers | Winfield Jr., Antoine | SS | Minnesota | |
| 46 | Denver Broncos | Hamler, KJ | WR | Penn State | |
| 47 | Atlanta Falcons | Davidson, Marlon | DE | Auburn | |
| 48 | Seattle Seahawks | Taylor, Darrell | OB | Tennessee | f/NYJ |
| 49 | Pittsburgh Steelers | Claypool, Chase | WR | Notre Dame | |
| 50 | Chicago Bears | Johnson, Jaylon | CB | Utah | |
| 51 | Dallas Cowboys | Diggs, Trevon | CB | Alabama | |
| 52 | Los Angeles Rams | Akers, Cam | RB | Florida State | |
| 53 | Philadelphia Eagles | Hurts, Jalen | QB | Oklahoma | |
| 54 | Buffalo Bills | Epenesa, AJ | DE | Iowa | |
| 55 | Baltimore Ravens | Dobbins, JK | RB | Ohio State | f/NE/Atl |
| 56 | Miami Dolphins | Davis, Raekwon | DE | Alabama | f/NO |
| 57 | Los Angeles Rams | Jefferson, Van | WR | Florida | f/Hou |
| 58 | Minnesota Vikings | Cleveland, Ezra | OT | Boise State | |
| 59 | New York Jets | Mims, Denzel | WR | Baylor | f/Sea |
| 60 | New England Patriots | Uche, Josh | OB | Michigan | f/Bal |
| 61 | Tennessee Titans | Fulton, Kristian | CB | LSU | |
| 62 | Green Bay Packers | Dillon, AJ | RB | Boston College | |
| 63 | Kansas City Chiefs | Gay Jr., Willie | OB | Mississippi State | f/SF |
| 64 | Carolina Panthers | Chinn, Jeremy | FS | Southern Illinois | f/KC/Sea |
| Round 3 |
| 65 | Cincinnati Bengals | Wilson, Logan | IB | Wyoming | |
| 66 | Washington Commanders | Gibson, Antonio | RB | Memphis | |
| 67 | Detroit Lions | Okwara, Julian | OB | Notre Dame | |
| 68 | New York Jets | Davis, Ashtyn | FS | California | f/NY Giants |
| 69 | Seattle Seahawks | Lewis, Damien | OG | LSU | f/Car |
| 70 | Miami Dolphins | Jones, Brandon | FS | Texas | |
| 71 | Baltimore Ravens | Madubuike, Justin | DT | Texas A&M | f/LAC/NE |
| 72 | Arizona Cardinals | Jones, Josh | OT | Houston | |
| 73 | Jacksonville Jaguars | Hamilton, Davon | DT | Ohio State | |
| 74 | New Orleans Saints | Baun, Zack | OB | Wisconsin | f/Cle |
| 75 | Detroit Lions | Jackson, Jonah | OG | Ohio State | f/Ind |
| 76 | Tampa Bay Buccaneers | Vaughn, Ke'Shawn | RB | Vanderbilt | |
| 77 | Denver Broncos | Ojemudia, Michael | CB | Iowa | |
| 78 | Atlanta Falcons | Hennessy, Matt | OC | Temple | |
| 79 | New York Jets | Zuniga, Jabari | DE | Florida | |
| 80 | Las Vegas Raiders | Bowden Jr., Lynn | WR | Kentucky | |
| 81 | Las Vegas Raiders | Edwards, Bryan | WR | South Carolina | f/Chi |
| 82 | Dallas Cowboys | Gallimore, Neville | DT | Oklahoma | |
| 83 | Denver Broncos | Cushenberry III, Lloyd | OC | LSU | f/Pit |
| 84 | Los Angeles Rams | Lewis, Terrell | OB | Alabama | |
| 85 | Indianapolis Colts | Blackmon, Julian | FS | Utah | f/Phi/Det |
| 86 | Buffalo Bills | Moss, Zack | RB | Utah | |
| 87 | New England Patriots | Jennings, Anfernee | OB | Alabama | |
| 88 | Cleveland Browns | Elliott, Jordan | DT | Missouri | f/NO |
| 89 | Minnesota Vikings | Dantzler, Cameron | CB | Mississippi State | |
| 90 | Houston Texans | Greenard, Jonathan | DE | Florida | |
| 91 | New England Patriots | Asiasi, Devin | TE | UCLA | f/Sea/Hou/LV |
| 92 | Baltimore Ravens | Duvernay, Devin | WR | Texas | |
| 93 | Tennessee Titans | Evans, Darrynton | RB | Appalachian State | |
| 94 | Green Bay Packers | Deguara, Josiah | TE | Cincinnati | |
| 95 | Denver Broncos | Agim, McTelvin | DT | Arkansas | f/SF |
| 96 | Kansas City Chiefs | Niang, Lucas | OT | TCU | |
| 97 | Cleveland Browns | Phillips, Jacob | IB | LSU | f/Hou |
| 98 | Baltimore Ravens | Harrison, Malik | IB | Ohio State | f/NE |
| 99 | New York Giants | Peart, Matt | OT | Connecticut | |
| 100 | Las Vegas Raiders | Muse, Tanner | OB | Clemson | f/NE |
| 101 | New England Patriots | Keene, Dalton | TE | Virginia Tech | f/Sea/NYJ |
| 102 | Pittsburgh Steelers | Highsmith, Alex | OB | UNC Charlotte | |
| 103 | Philadelphia Eagles | Taylor, Davion | OB | Colorado | |
| 104 | Los Angeles Rams | Burgess, Terrell | SS | Utah | |
| 105 | New Orleans Saints | Trautman, Adam | TE | Dayton | f/Min |
| 106 | Baltimore Ravens | Phillips, Tyre | OG | Mississippi State | |
| Round 4 |
| 107 | Cincinnati Bengals | Davis-Gaither, Akeem | OB | Appalachian State | |
| 108 | Washington Commanders | Charles, Saahdiq | OG | LSU | |
| 109 | Las Vegas Raiders | Simpson, John | OG | Clemson | f/Det |
| 110 | New York Giants | Holmes, Darnay | CB | UCLA | |
| 111 | Miami Dolphins | Kindley, Solomon | OG | Georgia | f/Hou |
| 112 | Los Angeles Chargers | Kelley, Joshua | RB | UCLA | |
| 113 | Carolina Panthers | Pride Jr., Troy | CB | Notre Dame | |
| 114 | Arizona Cardinals | Fotu, Leki | DT | Utah | |
| 115 | Cleveland Browns | Bryant, Harrison | TE | Florida Atlantic | |
| 116 | Jacksonville Jaguars | Bartch, Ben | OT | St. John's (MN) | |
| 117 | Minnesota Vikings | Wonnum, DJ | DE | South Carolina | f/TB/SF |
| 118 | Denver Broncos | Okwuegbunam, Albert | TE | Missouri | |
| 119 | Atlanta Falcons | Walker, Mykal | OB | Fresno State | |
| 120 | New York Jets | Perine, Lamical | RB | Florida | |
| 121 | Detroit Lions | Stenberg, Logan | OG | Kentucky | f/LV |
| 122 | Indianapolis Colts | Eason, Jacob | QB | Washington | |
| 123 | Dallas Cowboys | Robinson II, Reggie | CB | Tulsa | |
| 124 | Pittsburgh Steelers | McFarland Jr., Anthony | RB | Maryland | |
| 125 | New York Jets | Morgan, James | QB | Florida International | f/Chi/NE |
| 126 | Houston Texans | Heck, Charlie | OT | North Carolina | f/LAR |
| 127 | Philadelphia Eagles | Wallace, K'Von | SS | Clemson | |
| 128 | Buffalo Bills | Davis, Gabriel | WR | Central Florida | |
| 129 | New York Jets | Clark, Cameron | OG | UNC Charlotte | f/NE/Bal |
| 130 | Minnesota Vikings | Lynch, James | DT | Baylor | f/NO |
| 131 | Arizona Cardinals | Lawrence, Rashard | DT | LSU | f/Hou |
| 132 | Minnesota Vikings | Dye, Troy | IB | Oregon | |
| 133 | Seattle Seahawks | Parkinson, Colby | TE | Stanford | |
| 134 | Atlanta Falcons | Hawkins, Jaylinn | SS | California | f/Bal |
| 135 | Pittsburgh Steelers | Dotson, Kevin | OG | Louisiana | f/Ten/Mia |
| 136 | Los Angeles Rams | Hopkins, Brycen | TE | Purdue | f/GB/Mia/Hou |
| 137 | Jacksonville Jaguars | Scott, Josiah | CB | Michigan State | f/SF/Den |
| 138 | Kansas City Chiefs | Sneed, L'Jarius | FS | Louisiana Tech | |
| 139 | Las Vegas Raiders | Robertson, Amik | CB | Louisiana Tech | f/TB/NE |
| 140 | Jacksonville Jaguars | Quarterman, Shaquille | IB | Miami | f/Chi |
| 141 | Houston Texans | Reid, John | CB | Penn State | f/Mia |
| 142 | Washington Commanders | Gandy-Golden, Antonio | WR | Liberty | |
| 143 | Baltimore Ravens | Bredeson, Ben | OG | Michigan | |
| 144 | Seattle Seahawks | Dallas, DeeJay | RB | Miami | |
| 145 | Philadelphia Eagles | Driscoll, Jack | OG | Auburn | |
| 146 | Dallas Cowboys | Biadasz, Tyler | OC | Wisconsin | f/Phi |
| Round 5 |
| 147 | Cincinnati Bengals | Kareem, Khalid | DE | Notre Dame | |
| 148 | Seattle Seahawks | Robinson, Alton | DE | Syracuse | f/Was/Car |
| 149 | Indianapolis Colts | Pinter, Danny | OG | Ball State | f/Det |
| 150 | New York Giants | Lemieux, Shane | OG | Oregon | |
| 151 | Los Angeles Chargers | Reed, Joe | WR | Virginia | |
| 152 | Carolina Panthers | Robinson, Kenny | FS | West Virginia | |
| 153 | San Francisco 49ers | McKivitz, Colton | OT | West Virginia | f/Mia |
| 154 | Miami Dolphins | Strowbridge, Jason | DE | North Carolina | f/Jax/Pit |
| 155 | Chicago Bears | Gipson, Trevis | DE | Tulsa | f/Cle/Buf/Min |
| 156 | Washington Commanders | Ismael, Keith | OC | San Diego State | f/Den/SF |
| 157 | Jacksonville Jaguars | Thomas, Daniel | SS | Auburn | f/Atl/Bal |
| 158 | New York Jets | Hall, Bryce | CB | Virginia | |
| 159 | New England Patriots | Rohrwasser, Justin | PK | Marshall | f/LV |
| 160 | Cleveland Browns | Harris, Nick | OC | Washington | f/Ind |
| 161 | Tampa Bay Buccaneers | Johnson, Tyler | WR | Minnesota | |
| 162 | Washington Commanders | Hudson, Khaleke | OB | Michigan | f/Pit/Sea |
| 163 | Chicago Bears | Vildor, Kindle | CB | Georgia Southern | |
| 164 | Miami Dolphins | Weaver, Curtis | OB | Boise State | f/Dal/Phi |
| 165 | Jacksonville Jaguars | Johnson, Collin | WR | Texas | f/LAR |
| 166 | Detroit Lions | Cephus, Quintez | WR | Wisconsin | f/Phi |
| 167 | Buffalo Bills | Fromm, Jake | QB | Georgia | |
| 168 | Philadelphia Eagles | Hightower, John | WR | Boise State | f/NE |
| 169 | Minnesota Vikings | Hand, Harrison | CB | Temple | f/NO |
| 170 | Baltimore Ravens | Washington Jr., Broderick | DT | Texas Tech | f/MIN |
| 171 | Houston Texans | Coulter, Isaiah | WR | Rhode Island | |
| 172 | Detroit Lions | Huntley, Jason | RB | New Mexico State | f/Sea/NE/LV |
| 173 | Chicago Bears | Mooney, Darnell | WR | Tulane | f/Bal/LAR/Mia/Phi |
| 174 | Tennessee Titans | Murchison, Larrell | DT | North Carolina State | |
| 175 | Green Bay Packers | Martin, Kamal | OB | Minnesota | |
| 176 | Minnesota Vikings | Osborn, KJ | WR | Miami | f/SF |
| 177 | Kansas City Chiefs | Danna, Mike | OB | Michigan | |
| 178 | Denver Broncos | Strnad, Justin | OB | Wake Forest | |
| 179 | Dallas Cowboys | Anae, Bradlee | DE | Utah | |
| Round 6 |
| 180 | Cincinnati Bengals | Adeniji, Hakeem | OG | Kansas | |
| 181 | Denver Broncos | Muti, Netane | OG | Fresno State | f/Was |
| 182 | New England Patriots | Onwenu, Michael | OG | Michigan | f/Det/Ind |
| 183 | New York Giants | Brown, Cam | OB | Penn State | |
| 184 | Carolina Panthers | Roy, Bravvion | DT | Baylor | |
| 185 | Miami Dolphins | Ferguson, Blake | LS | LSU | |
| 186 | Los Angeles Chargers | Gilman, Alohi | SS | Notre Dame | |
| 187 | Cleveland Browns | Peoples-Jones, Donovan | WR | Michigan | f/Arz |
| 188 | Buffalo Bills | Bass, Tyler | PK | Georgia Southern | f/Cle |
| 189 | Jacksonville Jaguars | Luton, Jake | QB | Oregon State | |
| 190 | San Francisco 49ers | Woerner, Charlie | TE | Georgia | f/Atl/Phi |
| 191 | New York Jets | Mann, Braden | PT | Texas A&M | |
| 192 | Green Bay Packers | Runyan, Jon | OG | Michigan | f/LV |
| 193 | Indianapolis Colts | Windsor, Robert | DT | Penn State | |
| 194 | Tampa Bay Buccaneers | Davis, Khalil | DT | Nebraska | |
| 195 | New England Patriots | Herron, Justin | OG | Wake Forest | f/Den |
| 196 | Philadelphia Eagles | Bradley, Shaun | IB | Temple | f/Chi |
| 197 | Detroit Lions | Penisini, John | DT | Utah | f/Dal/Mia/Ind |
| 198 | Pittsburgh Steelers | Brooks Jr., Antoine | SS | Maryland | |
| 199 | Los Angeles Rams | Fuller, Jordan | FS | Ohio State | |
| 200 | Philadelphia Eagles | Watkins, Quez | WR | Southern Mississippi | f/Chi |
| 201 | Baltimore Ravens | Proche, James | WR | SMU | f/Buf/Min |
| 202 | Arizona Cardinals | Weaver, Evan | IB | California | f/NE |
| 203 | Minnesota Vikings | Brandel, Blake | OT | Oregon State | f/NO |
| 204 | New England Patriots | Maluia, Cassh | OB | Wyoming | f/Hou |
| 205 | Minnesota Vikings | Metellus, Josh | SS | Michigan | |
| 206 | Jacksonville Jaguars | Davis, Tyler | TE | Georgia Tech | f/Sea |
| 207 | Buffalo Bills | Hodgins, Isaiah | WR | Oregon State | f/Bal/NE |
| 208 | Green Bay Packers | Hanson, Jake | OC | Oregon | f/Ten |
| 209 | Green Bay Packers | Stepaniak, Simon | OG | Indiana | |
| 210 | Philadelphia Eagles | Wanogho, Prince Tega | OT | Auburn | f/SF |
| 211 | Indianapolis Colts | Rodgers, Isaiah | CB | Massachusetts | f/KC/NYJ |
| 212 | Indianapolis Colts | Patmon, Dezmon | WR | Washington State | f/NE |
| 213 | Indianapolis Colts | Glasgow, Jordan | OB | Michigan | f/NE |
| 214 | Seattle Seahawks | Swain, Freddie | WR | Florida | |
| Round 7 |
| 215 | Cincinnati Bengals | Bailey, Markus | IB | Purdue | |
| 216 | Washington Commanders | Curl, Kamren | SS | Arkansas | |
| 217 | San Francisco 49ers | Jennings, Jauan | WR | Tennessee | f/Det |
| 218 | New York Giants | Coughlin, Carter | OB | Minnesota | |
| 219 | Baltimore Ravens | Stone, Geno | SS | Iowa | f/Mia/Min |
| 220 | Los Angeles Chargers | Hill, KJ | WR | Ohio State | |
| 221 | Carolina Panthers | Thomas-Oliver III, Stantley | CB | Florida International | |
| 222 | Arizona Cardinals | Benjamin, Eno | RB | Arizona State | |
| 223 | Jacksonville Jaguars | Claybrooks, Chris | CB | Memphis | |
| 224 | Tennessee Titans | McDonald, Cole | QB | Hawaii | f/Cle |
| 225 | Minnesota Vikings | Willekes, Kenny | DE | Michigan State | f/NYJ/Bal |
| 226 | Chicago Bears | Hambright, Arlington | OG | Colorado | f/LV |
| 227 | Chicago Bears | Simmons, Lachavious | OG | Tennessee State | f/Ind/Mia/Phi |
| 228 | Atlanta Falcons | Hofrichter, Sterling | PT | Syracuse | f/TB/Phi |
| 229 | Washington Commanders | Smith-Williams, James | DE | North Carolina State | f/Den |
| 230 | New England Patriots | Woodard, Dustin | OC | Memphis | f/Atl |
| 231 | Dallas Cowboys | DiNucci, Ben | QB | James Madison | |
| 232 | Pittsburgh Steelers | Davis, Carlos | DT | Nebraska | |
| 233 | Philadelphia Eagles | Toohill, Casey | OB | Stanford | f/Chi |
| 234 | Los Angeles Rams | Johnston, Clay | IB | Baylor | |
| 235 | Detroit Lions | Cornell, Jashon | DT | Ohio State | f/Phi/NE |
| 236 | Green Bay Packers | Scott, Vernon | FS | TCU | f/Buf/Cle |
| 237 | Kansas City Chiefs | Keyes, Thakarius | CB | Tulane | f/NE/Den/Ten |
| 238 | New York Giants | Brunson, TJ | IB | South Carolina | f/NO |
| 239 | Buffalo Bills | Jackson, Dane | CB | Pittsburgh | f/Min |
| 240 | New Orleans Saints | Stevens, Tommy | QB | Mississippi State | f/Hou |
| 241 | Tampa Bay Buccaneers | Russell, Chapelle | OB | Temple | f/Sea/NE |
| 242 | Green Bay Packers | Garvin, Jonathan | DE | Miami | f/Bal |
| 243 | Tennessee Titans | Jackson, Chris | CB | Marshall | f/GB/Cle/NO |
| 244 | Minnesota Vikings | Stanley, Nate | QB | Iowa | |
| 245 | Tampa Bay Buccaneers | Calais, Raymond | RB | Louisiana | f/SF |
| 246 | Miami Dolphins | Perry, Malcolm | WR | Navy | f/KC |
| 247 | New York Giants | Williamson, Chris | CB | Minnesota | |
| 248 | Los Angeles Rams | Sloman, Sam | PK | Miami (OH) | f/Hou |
| 249 | Minnesota Vikings | Cole II, Brian | SS | Mississippi State | |
| 250 | Los Angeles Rams | Anchrum, Tremayne | OG | Clemson | f/Hou |
| 251 | Seattle Seahawks | Sullivan, Stephen | TE | LSU | f/Mia |
| 252 | Denver Broncos | Cleveland, Tyrie | WR | Florida | |
| 253 | Minnesota Vikings | Hinton, Kyle | OC | Washburn | |
| 254 | Denver Broncos | Tuszka, Derrek | DE | North Dakota State | |
| 255 | New York Giants | Crowder, Tae | IB | Georgia | |