| 1 | Sun, Sep 06 | vs  Louisville | W 41-38 | Nissan Stadium
Nashville, TN |
| 2 | Sat, Sep 12 | vs  Charlotte | W 41-9 | Vaught-Hemingway Stadium
Oxford, MS |
| 3 | Sat, Sep 19 | vs  11 LSU | W 32-24 | Vaught-Hemingway Stadium
Oxford, MS |
| 4 | Sat, Sep 26 | @  8 Florida | L 28-52 | Ben Hill Griffin Stadium at Florida Field
Gainesville, FL |
| 5 | Sat, Oct 03 | Open Date | |
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| 6 | Sat, Oct 10 | @  Vanderbilt | | Vanderbilt Stadium
Nashville, TN |
| 7 | Sat, Oct 17 | vs  25 Missouri | | Vaught-Hemingway Stadium
Oxford, MS |
| 8 | Sat, Oct 24 | @  1 Texas | | Darrell K Royal-Texas Memorial Stadium
Austin, TX |
| 9 | Sat, Oct 31 | vs  Auburn | | Vaught-Hemingway Stadium
Oxford, MS |
| 10 | Sat, Nov 07 | vs  2 Georgia | | Vaught-Hemingway Stadium
Oxford, MS |
| 11 | Sat, Nov 14 | @  Oklahoma | | Memorial Stadium at Owen Field
Norman, OK |
| 12 | Sat, Nov 21 | vs Wofford | | Vaught-Hemingway Stadium
Oxford, MS |
| 13 | Fri, Nov 27 | vs  16 Mississippi State | | Vaught-Hemingway Stadium
Oxford, MS |
| 14 | Sat, Dec 05 | Open Date | |
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