| Pos | No | Player 1 | No | Player 2 | No | Player 3 | No | Player 4 | No | Player 5 |
| Offense |
| LWR | 17 |
MCLAURIN, TERRY 19/3
| |
| |
| |
| |
|
| RWR | 19 |
MOORE, CHRIS SF24
| 13 |
Burks, Treylon SF25
| |
| |
| |
|
| SWR | 1 |
Samuel, Deebo T/SF
| 83 |
Lane, Jaylin 25/4
| |
| |
| |
|
| LT | 78 |
TUNSIL, LAREMY T/Hou
| 73 |
SCOTT, TRENT U/Pit
| |
| |
| |
|
| LG | 75 |
Paul, Chris 22/7
| 74 |
Coleman, Brandon 24/3
| |
| |
| |
|
| C | 63 |
Biadasz, Tyler U/Dal
| |
| |
| |
| |
|
| RG | 76 |
Cosmi, Sam 21/2
| 67 |
Allegretti, Nick U/KC
| |
| |
| |
|
| RT | 72 |
Conerly Jr., Josh 25/1
| 71 |
WYLIE, ANDREW U/KC
| 77 |
FANT, GEORGE CC/Sea
| |
| |
|
| TE | 86 |
ERTZ, ZACH SF24
| 87 |
Bates, John 21/4
| 82 |
Sinnott, Ben 24/2
| 80 |
Yankoff, Colson CF24
| |
|
| QB | 5 |
Daniels, Jayden 24/1
| 8 |
MARIOTA, MARCUS U/Phi
| 14 |
JOHNSON, JOSH U/Bal
| |
| |
|
| RB | 36 |
Rodriguez Jr., Chris 23/6
| 22 |
Croskey-Merritt, Jacory 25/7
| 26 |
McNichols, Jeremy SF24
| |
| |
|
| Defense |
| LDE | 55 |
Martin, Jacob U/Chi
| 59 |
Maguranyanga, T.J. SF25*
| 96 |
Holmes, Jalyn SF24
| |
| |
|
| LDT | 94 |
Payne, Daron 18/1
| 95 |
Newton, Jer'Zhan 24/2
| |
| |
| |
|
| RDT | 99 |
Kinlaw, Javon U/NYJ
| 97 |
GOLDMAN, EDDIE U/Atl
| 98 |
DAY, SHELDON U/Min
| |
| |
|
| RDE | 24 |
MILLER, VON CC/Buf
| 52 |
SMITH, PRESTON CC/Pit
| |
| |
| |
|
| WLB | 4 |
Luvu, Frankie U/Car
| 58 |
Magee, Jordan 24/5
| 57 |
BELLORE, NICK CC/Sea
| |
| |
|
| MLB | 54 |
WAGNER, BOBBY U/Sea
| 56 |
Medrano, Kain 25/6
| 51 |
Kaho, Ale CF25
| |
| |
|
| LCB | 0 |
Sainristil, Mike 24/2
| 34 |
HAMILTON SR., ANTONIO U/Atl
| |
| |
| |
|
| SS | 3 |
Harris, Will U/NO
| 39 |
Reaves, Jeremy SF18
| |
| |
| |
|
| FS | 20 |
Martin, Quan 23/2
| 35 |
Butler, Percy 22/4
| 25 |
Savage, Darnell SF25
| |
| |
|
| RCB | 31 |
JONES, JONATHAN U/NE
| |
| |
| |
| |
|
| NB | 6 |
Igbinoghene, Noah U/Dal
| 18 |
Owens, Tyler CF24
| |
| |
| |
|
| Special Teams |
| PT | 10 |
WAY, TRESS W/Chi
| |
| |
| |
| |
|
| PK | 16 |
Moody, Jake P/Chi
| |
| |
| |
| |
|
| LS | 69 |
OTT, TYLER U/Bal
| 45 |
TRINER, ZACH SF25
| |
| |
| |
|
| H | 10 |
WAY, TRESS W/Chi
| |
| |
| |
| |
|
| KO | 16 |
Moody, Jake P/Chi
| |
| |
| |
| |
|
| PR | 83 |
Lane, Jaylin 25/4
| 0 |
Sainristil, Mike 24/2
| |
| |
| |
|
| KR | 1 |
Samuel, Deebo T/SF
| 83 |
Lane, Jaylin 25/4
| |
| |
| |
|
| Practice Squad |
| WR | 84 |
Jones, Jacoby CF25
| 48 |
CRACRAFT, RIVER SF25
| |
| |
| |
|
| OT | |
| |
| |
| |
| |
|
| OG | 68 |
McKay, Timothy CF25
| |
| |
| |
| |
|
| C | 60 |
Deiter, Michael U/Hou
| 61 |
Good-Jones, Julian P/Phi
| |
| |
| |
|
| TE | 89 |
Cager, Lawrence SF25
| |
| |
| |
| |
|
| QB | 15 |
Hartman, Sam CF24
| |
| |
| |
| |
|
| RB | 32 |
Edwards, Donovan SF25
| 38 |
Edmonds, Chase U/TB
| |
| |
| |
|
| ED | 50 |
WALKER, DEMARCUS CC/Chi
| |
| |
| |
| |
|
| DI | 66 |
Barber, Ricky CF25
| |
| |
| |
| |
|
| LB | |
| |
| |
| |
| |
|
| CB | 22 |
Vigers, Car'lin CF25
| 29 |
Rush, Darius SF25
| 46 |
Hawkins III, Tre SF25
| |
| |
|
| S | 47 |
McDaniel, Robert CF25
| |
| |
| |
| |
|
| LS | |
| |
| |
| |
| |
|
| Reserves |
| IR | 90 |
Jean-Baptiste, Javontae DE^
| 11 |
McCaffrey, Luke WR^
| 23 |
Amos, Trey CB^
| 53 |
Niang, Lucas OT
| 30 |
EKELER, AUSTIN RB
|
| IR | 92 |
Armstrong, Dorance DE
| 2 |
Lattimore, Marshon CB
| 91 |
WISE JR., DEATRICH DE
| 80 |
Jackson, Tyree TE
| |
|
| DFR | 88 |
Brooks, Ja'Corey WR^
| |
| |
| |
| |
|
| DFR | 93 |
Jackson, Drake DE^
| 85 |
Brown, Noah WR^
| |
| |
| |
|