| Pos | No | Player 1 | No | Player 2 | No | Player 3 | No | Player 4 | No | Player 5 |
| Offense |
| LWR | 5 |
EVANS, MIKE U/TB
| 84 |
COOKS, BRANDIN U/Buf
| |
| |
| |
|
| RWR | 4 |
Cowing, Jacob 24/4
| |
| |
| |
| |
|
| SWR | 19 |
SAMUEL SR., DEEBO U/Was
| 17 |
Watkins, Jordan 25/4
| |
| |
| |
|
| LT | 71 |
WILLIAMS, TRENT T/Was
| 69 |
Cruz Jr., Enrique 26/5 IA
| |
| |
| |
|
| LG | 75 |
Colby, Connor 25/7
| 74 |
Willis, Carver 26/4
| |
| |
| |
|
| C | 64 |
BRENDEL, JAKE SF20
| 58 |
Patterson, Jarrett T/Hou
| |
| |
| |
|
| RG | 77 |
Puni, Dominick 24/3
| |
| |
| |
| |
|
| RT | 68 |
MCKIVITZ, COLTON 20/5
| 76 |
Lowe, Vederian U/NE
| |
| |
| |
|
| TE | 85 |
KITTLE, GEORGE 17/5
| 89 |
Farrell, Luke U/Jax
| 9 |
Willis, Brayden 23/7
| 83 |
Stoll, Jack SF26
| |
|
| QB | 13 |
Purdy, Brock 22/7
| 10 |
Jones, Mac U/Jax
| 14 |
Rourke, Kurtis 25/7 IA
| |
| |
|
| RB | 23 |
MCCAFFREY, CHRISTIAN T/Car
| 26 |
Black, Kaelon 26/3
| 29 |
James, Jordan 25/5
| |
| |
|
| FB | 44 |
JUSZCZYK, KYLE U/Bal O
| |
| |
| |
| |
|
| Defense |
| LDE | 56 |
White, Keion T/NE
| 98 |
Williams, Mykel 25/1
| 59 |
OKORONKWO, OGBO U/Phi
| |
| |
|
| LDT | 92 |
Odighizuwa, Osa T/Dal
| 96 |
Thompson Jr., James CF26 O
| 50 |
Jones, Naquan P/Min
| |
| |
|
| RDT | 93 |
Halton, Gracen 26/4
| 55 |
Valdez, Sebastian CF25
| |
| |
| |
|
| RDE | 97 |
Bosa, Nick 19/1 O
| 94 |
Height, Romello 26/3
| 47 |
Kareem, Khalid P/Atl
| |
| |
|
| WLB | 53 |
Dugger, Jaden 26/5
| 51 |
GIFFORD, LUKE U/Ten
| 48 |
Bethune, Tatum 24/7 IA
| |
| |
|
| MLB | 54 |
Warner, Fred 18/3
| 49 |
Wallow, Garret W/Den
| |
| |
| |
|
| LCB | 0 |
Green, Renardo 24/2
| 25 |
Jones, Jack U/Mia
| |
| |
| |
|
| SS | 36 |
Sigle, Marques 25/5 O
| 6 |
Mustapha, Malik 24/4
| 24 |
DAVIS, ASHTYN U/Mia
| |
| |
|
| FS | 27 |
Brown, Ji'Ayir 23/3
| 33 |
NEAL, SIRAN U/Mia
| |
| |
| |
|
| RCB | 2 |
Lenoir, Deommodore 21/5
| 28 |
Prysock, Ephesians 26/4
| |
| |
| |
|
| NB | 20 |
Stout, Upton 25/3
| |
| |
| |
| |
|
| Special Teams |
| PT | 15 |
WAITMAN, CORLISS U/Pit
| |
| |
| |
| |
|
| PK | 18 |
PIÑEIRO, EDDY U/Car
| |
| |
| |
| |
|
| LS | 46 |
WEEKS, JON U/Hou
| |
| |
| |
| |
|
| H | 15 |
WAITMAN, CORLISS U/Pit
| |
| |
| |
| |
|
| KO | 18 |
PIÑEIRO, EDDY U/Car
| |
| |
| |
| |
|
| PR | 4 |
Cowing, Jacob 24/4
| 17 |
Watkins, Jordan 25/4
| |
| |
| |
|
| KR | 19 |
SAMUEL SR., DEEBO U/Was
| 4 |
Cowing, Jacob 24/4
| 17 |
Watkins, Jordan 25/4
| |
| |
|
| Practice Squad |
| WR | 81 |
Grimes, Wesley CF26
| 18 |
Pauling, Will CF26
| 86 |
TURNER, MALIK SF24
| 15 |
Smith, Xavier SF26
| |
|
| OT | 67 |
Alarcon, Isaac SF24*
| 61 |
Sarell, Foster SF26
| |
| |
| |
|
| OG | |
| |
| |
| |
| |
|
| C | 66 |
Nugent, Drake CF24
| |
| |
| |
| |
|
| TE | 82 |
Dinkins, Khalil CF26
| |
| |
| |
| |
|
| QB | |
| |
| |
| |
| |
|
| RB | 35 |
McCormick, Sincere SF26
| |
| |
| |
| |
|
| ED | |
| 63 |
Fehoko Jr., Viliami SF26
| |
| |
| |
|
| DT | 65 |
Jackson, McKinnley SF26
| 90 |
Givens, Kevin CF19
| |
| |
| |
|
| LB | 41 |
Graham, Jalen P/Was
| |
| |
| |
| |
|
| CB | 40 |
Codrington, Brandon SF26
| |
| |
| |
| |
|
| S | 38 |
Stroman, Jalen CF26
| |
| |
| |
| |
|
| Reserves |
| IR | 11 |
ROBINSON, DEMARCUS WR^
| 99 |
West, C.J. DT^
| 88 |
Tonges, Jake TE^
| 7 |
Stribling, De'Zhaun WR^
| 95 |
Collins, Alfred DT^
|
| IR | 62 |
Pleasants, Austen OT^
| 22 |
Hobbs, Nate CB^
| 45 |
Martin, Nick LB^
| 91 |
Okuayinonu, Sam DE^
| 3 |
Kirk, Christian WR^
|
| IR | 1 |
Pearsall, Ricky WR
| 50 |
Farmer II, Andrew DE
| 59 |
Kamara, Mikail DE
| 63 |
Zakelj, Nick OG
| 29 |
Forrest, Darrick S
|
| IR | 78 |
TOTH, BRETT OG
| |
| |
| |
| |
|
| PUP | 31 |
Guerendo, Isaac RB^
| |
| |
| |
| |
|
| LEFT | 11 |
Aiyuk, Brandon WR
| |
| |
| |
| |
|
| SUS | 57 |
Greenlaw, Dre LB^
| |
| |
| |
| |
|