| Pos | No | Player 1 | No | Player 2 | No | Player 3 | No | Player 4 | No | Player 5 |
| Offense |
| LWR | 12 |
Boston, Denzel 26/2
| 11 |
Corley, Malachi SF25
| |
| |
| |
|
| RWR | 3 |
Jeudy, Jerry T/Den
| 16 |
Wallace, Tylan U/Bal O
| |
| |
| |
|
| SWR | 1 |
Concepcion Jr., KC 26/1
| 0 |
Bond, Isaiah CF25
| |
| |
| |
|
| LT | 55 |
Fano, Spencer 26/1
| 79 |
Jones, Dawand 23/4
| |
| |
| |
|
| LG | 77 |
Johnson, Zion U/LAC
| 70 |
Zinter, Zak 24/3
| |
| |
| |
|
| C | 74 |
JENKINS, ELGTON CC/GB O
| 56 |
Wypler, Luke 23/6
| 52 |
Brailsford, Parker 26/5
| |
| |
|
| RG | 78 |
Jenkins, Teven U/Chi O
| 58 |
Barber, Austin 26/3
| |
| |
| |
|
| RT | 71 |
HOWARD, TYTUS T/Hou
| |
| |
| |
| |
|
| TE | 44 |
Fannin Jr., Harold 25/3
| 86 |
Whiteheart, Blake SF24
| 48 |
Ryan, Carsen 26/7
| |
| |
|
| QB | 4 |
WATSON, DESHAUN T/Hou
| 2 |
Sanders, Shedeur 25/5
| 15 |
Green, Taylen 26/6
| |
| |
|
| RB | 10 |
Judkins, Quinshon 25/2
| 23 |
Sanders, Raheim W/LAC
| 38 |
McLaughlin, Jaleel SF26
| |
| |
|
| FB | 34 |
BURTON, MICHAEL U/Den
| |
| |
| |
| |
|
| Defense |
| LDE | 8 |
Verse, Jared T/LAR
| 54 |
Williams, Sam SF26
| |
| |
| |
|
| LDT | 96 |
COLLINS, MALIEK CC/SF
| 51 |
Hall Jr., Mike 24/2 Q
| |
| |
| |
|
| RDT | 94 |
Graham, Mason 25/1 O
| 98 |
Huntington, Adin CF25
| |
| |
| |
|
| RDE | 57 |
McGuire, Isaiah 23/4
| 97 |
BARNETT, DEREK U/Hou
| |
| |
| |
|
| WLB | 49 |
Schwesinger, Carson 25/2
| 42 |
Mascarenas-Arnold, Easton CF25
| |
| |
| |
|
| MLB | 5 |
WILLIAMS, QUINCY U/NYJ
| 59 |
Reid, Winston CF24
| 17 |
Jefferson, Justin 26/5
| |
| |
|
| LCB | 21 |
Ward, Denzel 18/1
| 35 |
Pride Jr., Toriano W/Buf
| |
| |
| |
|
| SS | 9 |
Delpit, Grant 20/2
| 31 |
McMillon, Donovan CF25
| 24 |
Thomas, Daniel U/Det
| |
| |
|
| FS | 33 |
Hickman, Ronnie CF23
| 28 |
McNeil-Warren, Emmanuel 26/2
| |
| |
| |
|
| RCB | 7 |
Campbell, Tyson T/Jax
| 29 |
Blackmon, Mekhi W/Ind
| |
| |
| |
|
| NB | 26 |
Harden, Myles 24/7
| 20 |
Igbinoghene, Noah SF26
| |
| |
| |
|
| Special Teams |
| PT | 13 |
BOJORQUEZ, COREY U/GB
| |
| |
| |
| |
|
| PK | 25 |
Szmyt, Andre SF24
| |
| |
| |
| |
|
| LS | 50 |
SUNAHARA, REX SF24
| |
| |
| |
| |
|
| H | 13 |
BOJORQUEZ, COREY U/GB
| |
| |
| |
| |
|
| KO | 25 |
Szmyt, Andre SF24
| |
| |
| |
| |
|
| PR | 1 |
Concepcion Jr., KC 26/1
| 12 |
Boston, Denzel 26/2
| 0 |
Bond, Isaiah CF25
| |
| |
|
| KR | 23 |
Sanders, Raheim W/LAC
| 11 |
Corley, Malachi SF25
| |
| |
| |
|
| Practice Squad |
| WR | 81 |
Means, Bub SF26
| 19 |
Horn Jr., Jimmy SF26
| |
| |
| |
|
| OT | 72 |
Leveston, KT T/LAR
| 68 |
Eze, Obinna U/Mia*
| |
| |
| |
|
| OG | 67 |
Truss, Xavier SF26
| |
| |
| |
| |
|
| C | |
| |
| |
| |
| |
|
| TE | 87 |
FitzPatrick, John U/GB
| |
| |
| |
| |
|
| QB | |
| |
| |
| |
| |
|
| RB | 41 |
Gray, Eric SF26
| |
| |
| |
| |
|
| ED | 99 |
Fano, Logan CF26
| 90 |
Sydnor, Khordae CF26
| 60 |
Tucker, Nadame SF26
| |
| |
|
| DT | 92 |
Kamara, Sam SF22
| 69 |
Logue, Zion SF26
| |
| |
| |
|
| LB | 43 |
Barnes, Krys SF26
| |
| |
| |
| |
|
| CB | 39 |
Coats Jr., Michael CF26
| 27 |
Bryant, Myles U/Hou
| |
| |
| |
|
| S | 30 |
Washington, Zion CF26
| |
| |
| |
| |
|
| PT | 36 |
Pahl, Wes CF26
| |
| |
| |
| |
|
| Reserves |
| IR | 22 |
Sampson, Dylan RB^
| 6 |
Gabriel, Dillon QB^
| 93 |
Davis, Kalia DT^
| 37 |
Mathis, Damarri CB
| 91 |
Wright, Alex DE
|
| IR | 54 |
Ulofoshio, Edefuan LB
| 62 |
Chatman, Elijah DT
| |
| |
| |
|
| PS/IR | 40 |
Watson, Nathaniel LB^
| |
| |
| |
| |
|
| PUP | 6 |
Owusu-Koramoah, Jeremiah LB
| |
| |
| |
| |
|
| NFI | 18 |
Royer, Joe TE^
| |
| |
| |
| |
|